ALEXANDRIA, Va., Oct. 6 -- United States Patent no. 12,753,149, issued on Oct. 6, was assigned to KOS THERAPEUTICS INC. (Raleigh, N.C.).

"N-formylhydroxylamines as neprilysin (NEP) inhibitors, in particular as mixed aminopeptidase N (APN) and neprilysin (NEP) inhibitors" was invented by Herve Poras (Villepreux, France), Marie-Claude Fournie-Zaluski (Paris) and Bernard Roques (Paris).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a compound of following formula (1):as well as a pharmaceutically acceptable salt and/or solvate thereof.The present invention also pertains to a pharmaceutical composition comprising at least one compound of formula (1) and at least one pharmaceutical...