ALEXANDRIA, Va., March 24 -- United States Patent no. 12,584,140, issued on March 24, was assigned to KEYGENE N.V. (Wageningen, Netherlands).
"Type V CRISPR/nuclease-system for genome editing in plant cells" was invented by Paul Bundock (AE Wageningen, Netherlands).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided is a method for targeted modification of DNA in a plant cell using crRNA-guided MAD7-nuclease and compositions and kits for doing the same. Preferably, the MAD7-nuclease comprises two catalytically active endonuclease domains or comprises at least one catalytically inactive endonuclease domain. Furthermore, the MAD7-endonuclease may be fused to a functional domain, such as a deaminase domain."...