ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,698,339, issued on Aug. 4, was assigned to Keio University (Tokyo) and Iwate Medical University (Iwate, Japan).
"Anti-glypican-1-immunizing antigen receptor" was invented by Tomonori Yaguchi (Tokyo), Kenji Morii (Tokyo), Yutaka Kawakami (Tokyo), Daiki Kato (Tokyo), Tetsuji Naka (Ibaraki, Japan), Satoshi Serada (Ibaraki, Japan) and Minoru Fujimoto (Ibaraki, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "The purpose of the present invention is to produce a chimeric antigen receptor (CAR) specific to glypican-1 (GPC-1) and to treat squamous cell carcinoma with genetically modified cells capable of expressing the CAR. The present invention provides: a ...