ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,225, issued on March 17, was assigned to Karyopharm Therapeutics Inc. (Newton, Mass.).

"Nuclear transport modulators and uses thereof" was invented by Erkan Baloglu (Stoneham, Mass.), Sharon Shacham (Newton, Mass.), Dilara McCauley (Arlington, Mass.), Trinayan Kashyap (Framingham, Mass.), William Senapedis (Millis, Mass.), Yosef Landesman (Brookline, Mass.), Gali Golan (Mesilat Zion, Israel), Ori Kalid (Pardes Hanna, Israel) and Sharon Shechter (Andover, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to compounds of formula I:and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising th...