US Patent Issued to Kansas State University Research Foundation on Dec. 2 for "Insect extracellular vesicles for delivery of nucleic acids" (Kansas Inventors)

ALEXANDRIA, Va., Dec. 2 -- United States Patent no. 12,486,520, issued on Dec. 2, was assigned to Kansas State University Research Foundation (Manhattan, Kan.).

"Insect extracellular vesicles for delivery of nucleic acids" was invented by Kristopher Silver (Manhattan, Kan.) and Yoonseong Park (Manhattan, Kan.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Nucleic acid delivery vehicles for delivering nucleic acid, e.g., for RNAi to cells that are typically refractory to RNAi by using extracellular vesicles (EVs) from cultured beetle cells as delivery vehicles. Instead of using high levels of long dsRNA and transfection reagents to accomplish suppression of an mRNA target in cells that don't respond to treatm...