ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,703,734, issued on Aug. 11, was assigned to Juno Therapeutics Inc. (Seattle).
"Method of assessing activity of recombinant antigen receptors" was invented by Rupesh Amin (Seattle) and Aye Chen (Seattle).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods for screening for one or more activity of a recombinant receptor, including recombinant receptors containing an extracellular antigen-binding domain and an intracellular signaling domain, such as a chimeric antigen receptor (CAR). The methods include assessing activity of a cell expressing the recombinant receptor based on a detectable expression of a reporter molecule that is resp...