ALEXANDRIA, Va., March 24 -- United States Patent no. 12,584,106, issued on March 24, was assigned to JSR Corp. (Tokyo) and KEIO UNIVERSITY (Tokyo).
"Method for producing oligodendrocyte-like cells" was invented by Mitsuru Ishikawa (Tokyo) and Hideyuki Okano (Tokyo).
According to the abstract* released by the U.S. Patent & Trademark Office: "A method is provided for producing oligodendrocyte-like cells, including (A) increasing abundances of oligodendrocyte transcription factor 2 (OLIG2) mutant and SRY-box transcription factor 10 (SOX10) in human pluripotent stein cells and (B) culturing the human pluripotent stem cells in which the abundances of the OLIG2 mutant and the SOX10 are increased and consequently differentiating the human pluri...