ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,734,202, issued on Sept. 15, was assigned to JOINT BIOSCIENCES (SH) LTD. (Shanghai).

"Oncolytic virus in combination with immune checkpoint inhibitor for treating tumors" was invented by Guoqing Zhou (Shanghai), He Yang (Shanghai), Fan Zhang (Shanghai) and Suhong Zhang (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present application relates to a medicine for treating tumors. A novel attenuated oncolytic virus strain is provided by means of a site-directed mutation of a wild-type virus matrix protein M of a vesicular stomatitis virus. On the basis of the attenuated oncolytic virus strain, an oncolytic virus vaccine is provided by inserti...