US Patent Issued to Jiangnan University on Feb. 17 for "Compound for specifically enhancing spatial coupling degree of TRPV4-KCa2.3 complex and use thereof" (Chinese Inventors)

ALEXANDRIA, Va., Feb. 17 -- United States Patent no. 12,552,773, issued on Feb. 17, was assigned to Jiangnan University (Wuxi, China).

"Compound for specifically enhancing spatial coupling degree of TRPV4-KCa2.3 complex and use thereof" was invented by Xin Ma (Wuxi, China), Chunlei Tang (Wuxi, China) and Shaying Yang (Wuxi, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a compound for specifically enhancing the spatial coupling degree of a TRPV4-KCa2.3 complex and use thereof, and belongs to the field of chemical medicine. The compound with a structure shown in a general formula (I) in the present disclosure is mainly used for re-coupling two uncoupled proteins and resto...