ALEXANDRIA, Va., Dec. 2 -- United States Patent no. 12,486,498, issued on Dec. 2, was assigned to JIANGNAN UNIVERSITY (Wuxi, China).

"L-arginine-glycine amidinotransferase and use thereof in the production of guanidinoacetic acid" was invented by Meijuan Xu (Wuxi, China), Zhiming Rao (Wuxi, China), Yaxin Liao (Wuxi, China), Haofei Xu (Wuxi, China), Xian Zhang (Wuxi, China) and Taowei Yang (Wuxi, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention discloses an L-arginine-glycine amidinotransferase and use thereof in the production of guanidinoacetic acid. In the present invention, through combined multi-site amino acid mutation, a technical effect of significantly improved enzyme activi...