US Patent Issued to JAPAN SCIENCE AND TECHNOLOGY AGENCY on July 14 for "Innovative production technique for antibody-enzyme" (Japanese Inventors)

ALEXANDRIA, Va., July 14 -- United States Patent no. 12,679,883, issued on July 14, was assigned to JAPAN SCIENCE AND TECHNOLOGY AGENCY (Saitama, Japan).

"Innovative production technique for antibody-enzyme" was invented by Taizo Uda (Oita, Japan) and Emi Hifumi (Oita, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for producing a Kappa light chain antibody having enzyme activity or improved enzyme activity includes modifying a polynucleotide that encodes a Kappa light chain antibody having a polypeptide having an amino acid sequence where the 95th amino acid residue from the N-terminal of a variable region by the Kabat classification is a proline residue, to delete or substitute the proline r...