US Patent Issued to Janssen Pharmaceutica on July 15 for "Processes and intermediates for preparing a Btk inhibitor" (Belgian, Dutch, Swiss Inventors)

ALEXANDRIA, Va., July 16 -- United States Patent no. 12,358,917, issued on July 15, was assigned to Janssen Pharmaceutica NV (Beerse, Belgium).

"Processes and intermediates for preparing a Btk inhibitor" was invented by Cyril Ben Haim (Vosselaar, Belgium), Thomas Joost Martti Michiels (Leiden, Netherlands), Florian Damien Medina (Brussels), Simon Albert Wagschal (Schaffhausen, Switzerland) and Dominique Paul M. Depre (Hamme-Mille, Belgium).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed is a process for the preparation of certain intermediates, e.g. the following compound:which intermediate and processes are useful in the preparation of a BTK inhibitor, such as ibrutinib."

The patent was filed on Ap...