ALEXANDRIA, Va., Aug. 25 -- United States Patent no. 12,715,878, issued on Aug. 25, was assigned to Janssen Pharmaceutica NV (Beerse, Belgium).

"Tricyclic pyrimidines as cyclin-dependent kinase 7 (CDK7) inhibitors" was invented by Ian Stansfield (Saint-Germain-en-Laye, France), Yannick Aime Eddy Ligny (Sotteville-les-Rouen, France), Yvan Rene Ferdinand Simonnet (Princeton, N.J.) and Nathalie Claudie Isabelle Amblard (Crestot, France).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to pharmaceutical compounds of formula (I) and pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds as inhibitors of cyclin-d...