US Patent Issued to Isofol Medical on Jan. 20 for "[6R-MTHF-an efficient folate alternative in 5-fluorouracil based chemotherapy" (Swedish Inventors)

ALEXANDRIA, Va., Jan. 20 -- United States Patent no. 12,527,796, issued on Jan. 20, was assigned to Isofol Medical AB (Gothenburg, Sweden).

"[6R-MTHF-an efficient folate alternative in 5-fluorouracil based chemotherapy" was invented by Per L. Lindberg (Gothenburg, Sweden), Anders Vedin (Gothenburg, Sweden), Gunnel E. Sunden (Gothenburg, Sweden) and Bengt Gustavsson (Vastra Froelunda, Sweden).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to the treatment of solid tumors in humans such as cancer, especially colorectal cancer (CRC), which involves administering the diastereomerically pure folate adjuvant [6R]-5, 10-methylenetetrahydrofolate in 5-fluorouracil (5-FU) based chemothera...