US Patent Issued to Iovance Biotherapeutics on Dec. 16 for "Closed process for expansion and gene editing of tumor infiltrating lymphocytes and uses of same in immunotherapy" (California, Florida Inventors)

ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,495,791, issued on Dec. 16, was assigned to Iovance Biotherapeutics Inc. (San Carlos, Calif.).

"Closed process for expansion and gene editing of tumor infiltrating lymphocytes and uses of same in immunotherapy" was invented by Cecile Chartier-Courtaud (Palo Alto, Calif.) and Krit Ritthipichai (Tampa, Fla.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a sho...