US Patent Issued to IONIS PHARMACEUTICALS on Sept. 22 for "Compounds and methods for reducing PLN expression" (California Inventors)

ALEXANDRIA, Va., Sept. 24 -- United States Patent no. 12,742,170, issued on Sept. 22, was assigned to IONIS PHARMACEUTICALS INC. (Carlsbad, Calif.).

"Compounds and methods for reducing PLN expression" was invented by Adam Mullick (Carlsbad, Calif.), Huynh-Hoa Bui (Carlsbad, Calif.), Susan M. Freier (Carlsbad, Calif.), Ting Yuan Yeh (Carlsbad, Calif.) and Dieter Kubli (Carlsbad, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are oligomeric agents, oligomeric compounds, methods, and pharmaceutical compositions for reducing the amount or activity of PLN RNA in a cell or animal, and in certain instances reducing the amount of PLN protein in a cell or animal. Such oligomeric agents, oligomeric com...