US Patent Issued to Ionis Pharmaceuticals on Nov. 3 for "Oligomer-conjugate complexes and their use" (California Inventors)

ALEXANDRIA, Va., Nov. 3 -- United States Patent no. 12,781,222, issued on Nov. 3, was assigned to Ionis Pharmaceuticals Inc. (Carlsbad, Calif.).

"Oligomer-conjugate complexes and their use" was invented by Thazha P. Prakash (Carlsbad, Calif.), Eric E. Swayze (Encinitas, Calif.), Walter F. Lima (San Diego) and Garth A. Kinberger (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "Oligonucleotides, chemically-modified oligonucleotides, and oligonucleotide-conjugate complexes for use in research, diagnostics, and/or therapeutics are described herein. In some embodiments, oligonucleotides comprising a stabilized phosphate moiety covalently attached to the 5'-terminal nucleoside are provided."

The patent w...