US Patent Issued to Ionis Pharmaceuticals on May 13 for "Modulation of huntingtin expression" (California, Massachusetts Inventors)

ALEXANDRIA, Va., June 12 -- United States Patent no. 12,297,431, issued on May 13, was assigned to Ionis Pharmaceuticals Inc. (Carlsbad, Calif.).

"Modulation of huntingtin expression" was invented by Gene Hung (Carlsbad, Calif.), C. Frank Bennet (Carlsbad, Calif.), Susan M. Freier (San Diego), Holly Kordasiewicz (San Diego), Lisa Stanek (Cambridge, Mass.), Don W. Cleveland (Del Mar, Calif.), Seng H. Cheng (Natick, Mass.) and Lamya Shihabuddin (Brighton, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods, compounds, and compositions for reducing expression of huntingtin mRNA and protein in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, o...