US Patent Issued to Ionis Pharmaceuticals, The Hospital for Sick Children on Aug. 25 for "Modulation of GYS1 expression" (Canadian, American Inventors)

ALEXANDRIA, Va., Aug. 25 -- United States Patent no. 12,716,067, issued on Aug. 25, was assigned to Ionis Pharmaceuticals Inc. (Carlsbad, Calif.) and The Hospital for Sick Children (Toronto).

"Modulation of GYS1 expression" was invented by Tamar R. Grossman (La Jolla, Calif.), Susan M. Freier (San Diego), Berge Minassian (Toronto) and Saija Ahonen (Toronto).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods, compounds, and compositions for reducing expression of GYS1 in an individual. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate a glycogen storage disease or disorder in an individual in need."

The patent was filed on June 8, 2023, under ...