US Patent Issued to Ionis Pharmaceuticals, Carlsbad on Sept. 9 for "Modulating apolipoprotein (A) expression" (California Inventors)

ALEXANDRIA, Va., Sept. 10 -- United States Patent no. 12,410,430, issued on Sept. 9, was assigned to Ionis Pharmaceuticals Inc. and Carlsbad Inc..

"Modulating apolipoprotein (A) expression" was invented by Nicholas J. Viney (Carlsbad, Calif.), Richard S. Geary (Carlsbad, Calif.), Yanfeng Wang (Carlsbad, Calif.) and Zhengrong Yu (Carlsbad, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are oligomeric compounds with conjugate groups targeting apoplipoprotein (a) [apo(a)]. In certain embodiments, the apo(a) targeting oligomeric compounds are conjugated to N-Acetylgalactosamine. Also disclosed herein are conjugated oligomeric compounds targeting apo(a) for use in decreasing apo(a) to treat...