US Patent Issued to Intellia Therapeutics on Sept. 15 for "Modified guide RNAs" (North Carolina, Massachusetts Inventors)

ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,735,698, issued on Sept. 15, was assigned to Intellia Therapeutics Inc. (Cambridge, Mass.).

"Modified guide RNAs" was invented by Amy Madison Rhoden Smith (Durham, N.C.), David V. Morrissey (Winchester, Mass.) and Walter Strapps (Dedham, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure relates to modified single and dual guide RNAs having improved in vitro and in vivo activity in gene editing methods."

The patent was filed on July 1, 2025, under Application No. 19/256,778.

*For further information, including images, charts and tables, please visit: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml...