US Patent Issued to Intellia Therapeutics on July 21 for "Compositions and methods comprising a TTR guide RNA and a polynucleotide encoding an RNA-guided DNA binding agent" (Massachusetts, New Hampshire Inventors)

ALEXANDRIA, Va., July 21 -- United States Patent no. 12,686,876, issued on July 21, was assigned to Intellia Therapeutics Inc. (Cambridge, Mass.).

"Compositions and methods comprising a TTR guide RNA and a polynucleotide encoding an RNA-guided DNA binding agent" was invented by Yong Chang (Acton, Mass.), Seth C. Alexander (Medford, Mass.), Kristy M. Wood (Wellesley, Mass.), Arti Mahendra Prakash Kanjolia (Malden, Mass.), Shobu Odate (Arlington, Mass.), Jessica Lynn Seitzer (Windham, N.H.), Reynald Michael Lescarbeau (Medford, Mass.) and Walter Strapps (Dedham, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods for editing, e.g., introducing double-stranded breaks, within the TTR ge...