US Patent Issued to INTEGRATED DNA TECHNOLOGIES on March 17 for "Aptamers for the reversible inhibition of DNA polymerases" (Iowa Inventors)

ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,569, issued on March 17, was assigned to INTEGRATED DNA TECHNOLOGIES INC. (Coralville, Iowa).

"Aptamers for the reversible inhibition of DNA polymerases" was invented by Susan Marie Rupp (Marion, Iowa), Shambhavi Shubham (Coralville, Iowa), Scott Rose (Coralville, Iowa) and Brianna Cagle (Iowa City, Iowa).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are methods and compositions for improved polymerase chain reaction (PCR). In one aspect the methods and compositions include improved aptamers to reversibly inhibit polymerase and exonuclease activity of the polymerase enzyme."

The patent was filed on Nov. 21, 2022, under Application...