ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,496,466, issued on Dec. 16, was assigned to Insightec Ltd. (Tirat Carmel, Israel).

"Simulation-based drug treatment planning" was invented by Yoav Levy (Hinanit, Israel), Rafi De Picciotto (Tirat Carmel, Israel), Javier Grinfeld (Tel Aviv-Jaffa, Israel) and Eyal Zadicario (Tel Aviv-Jaffa, Israel).

According to the abstract* released by the U.S. Patent & Trademark Office: "Various approaches for computationally generating a protocol for treatment of one or more target BBB regions within a tissue region of interest using a source of focused ultrasound include specifying (i) settings of sonication parameters for applying one or more sequence of sonications to the target BBB region using...