US Patent Issued to INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), UNIVERSITE PARIS-SACLAY on Feb. 24 for "Methods of treating bleeding disorders by administration of chimeras comprising anti-von Willebrand factor antibodies and clotting factors" (French Inventors)

ALEXANDRIA, Va., Feb. 24 -- United States Patent no. 12,559,569, issued on Feb. 24, was assigned to INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (Paris) and UNIVERSITE PARIS-SACLAY (St. Aubin, France).

"Methods of treating bleeding disorders by administration of chimeras comprising anti-von Willebrand factor antibodies and clotting factors" was invented by Petrus Lenting (Kremlin-Bicetre, France), Gabriel Ayme (Le Kremlin Bicetre, France), Cecile Denis (Le Kremlin-Bicetre, France) and Olivier Christophe (Le Kremlin-Bicetre, France).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to isolated single-domain antibodies (sdAb) directed against von Willebrand Factor (VWF) ...