ALEXANDRIA, Va., Aug. 18 -- United States Patent no. 12,709,737, issued on Aug. 18, was assigned to Innovative Cellular Therapeutics Holdings Ltd. (George Town, Cayman Islands) and Innovative Cellular Therapeutics Inc. (Rockville, Md.).
"Enhanced chimeric antigen receptor cells in hypoxic tumor microenvironment" was invented by Xiaogang Shen (Shanghai), Xudong Tang (Shanghai), Chengfei Pu (Shanghai), Lei Xiao (Rockville, Md.) and Le Tian (Rockville, Md.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Embodiments of the present disclosure relate to compositions and methods of enhancing lymphocytes' ability to treat cancer patients. Embodiments relate to a polynucleotide comprising a nucleic acid encoding a chi...