ALEXANDRIA, Va., April 7 -- United States Patent no. 12,594,343, issued on April 7, was assigned to INNATE PHARMA (Marseilles, France).
"Treatment of cancer" was invented by Manel Kraiem (Marseilles, France).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides antigen-binding proteins capable of binding to Nectin-4 polypeptides conjugated to chemotherapeutic agents, for use in increasing sensitivity of tumors to the chemotherapeutic agents, for use in the treatment of cancers characterized by Nectin expressing tumor cells. In one embodiment, the present invention provides conjugates of an anti-Nectin-4 antibody to a camptothecin analogue, such as exatecan or SN-38, through a cleavable...