US Patent Issued to INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY on Aug. 11 for "Ku inhibitors and their use" (Indiana Inventors)

ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,703,695, issued on Aug. 11, was assigned to INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY Corp. (Indianapolis).

"Ku inhibitors and their use" was invented by John J Turchi (Indianapolis), Navnath Gavande (Indianapolis) and Pamela S. Vandervere-Carozza (Zionsville, Ind.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to certain compounds having binding affinity for Ku, and uses thereof. Specifically, the present disclosure relates to the use of Ku inhibitors as described herein in site-specific genome engineering technologies, including but not limited to CRISPR/Cas9, Zinc finger nuclease (ZFN), Transcription activator-like eff...