ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,534, issued on March 17, was assigned to IMPERIAL COLLEGE INNOVATIONS Ltd. (London).
"Transduction and expansion of cells" was invented by Anastasios Karadimitris (London) and Antonia Rotolo (London).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided is a method of transducing and expanding a population of cells, the method comprising, in order: a cell selection step; a pre-transduction activation step; a cell transduction step; and a cell expansion phase. At least the cell transduction step and the expansion phase comprise incubation of the cells with IL-15. The methods of the invention are well suited to the transduction and expansion of popu...