ALEXANDRIA, Va., July 7 -- United States Patent no. 12,673,088, issued on July 7, was assigned to IMMUTEP S.A.S. (Orsay, France).
"Combined preparations for the treatment of cancer or infection" was invented by Frederic Triebel (Versailles, France) and Chrystelle Brignone (Chatenay-Malabry, France).
According to the abstract* released by the U.S. Patent & Trademark Office: "Combined preparations, and pharmaceutical compositions, comprising: (a) LAG-3 protein, or a derivative thereof that is able to bind to MHC class II molecules; and (b) a programmed cell death protein-1 (PD-1) pathway inhibitor, are described. The PD-1 pathway inhibitor, such as an anti-PD-1 antibody or an anti-PD-L1 antibody, and a soluble derivative of LAG-3, acting as...