ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,747,250, issued on Sept. 29, was assigned to IMMUNOGEN INC. (Waltham, Mass.).

"Camptothecin derivatives" was invented by Ravi V.J. Chari (Newton, Mass.), Wayne C. Widdison (Belmont, Mass.), Wei Li (Acton, Mass.) and David P. Pleynet (Newton, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are novel cytotoxic compounds, and cytotoxic conjugates comprising these cytotoxic compounds and cell-binding agents. More specifically, this disclosure relates to novel camptothecin derivatives thereof, intermediates thereof, conjugates thereof, and pharmaceutically acceptable salts thereof, which are useful as medicaments, in particular as anti...