US Patent Issued to Illumina on Oct. 27 for "Methods for chemical cleavage of surface-bound polynucleotides" (British Inventors)

ALEXANDRIA, Va., Oct. 27 -- United States Patent no. 12,774,493, issued on Oct. 27, was assigned to Illumina Inc. (San Diego).

"Methods for chemical cleavage of surface-bound polynucleotides" was invented by Oliver Miller (Cambridge, Great Britain), Pietro Marafini (Cambridge, Great Britain) and Alix Kwasniewska (Cambridge, Great Britain).

According to the abstract* released by the U.S. Patent & Trademark Office: "Embodiments of the present disclosure relate to modified extension primers for use in generating clustered polynucleotides for sequencing by synthesis. In particular, the disclosure relates to methods of chemically linearizing clustered polynucleotides in preparation for sequencing by cleavage of one or more strands of double-st...