ALEXANDRIA, Va., June 12 -- United States Patent no. 12,297,221, issued on May 13, was assigned to Illumina Inc. (San Diego).
"Functionalization and purification of molecules by reversible group exchange" was invented by Frank J. Steemers (Encinitas, Calif.), Kevin L. Gunderson (Encinitas, Calif.), Kerri York (Elizabeth, Colo.) and Ryan Christopher Smith (San Diego).
According to the abstract* released by the U.S. Patent & Trademark Office: "Embodiments of the present disclosure include methods and compositions for functionalizing molecules, such as oligonucleotides, with functional groups, including polyhistidine tags useful in affinity methods. Some embodiments include methods for modifying and purifying complex mixtures of molecules by...