ALEXANDRIA, Va., March 24 -- United States Patent no. 12,582,988, issued on March 24, was assigned to ILLUMINA INC. (San Diego).

"Actuation systems and methods for use with flow cells" was invented by Paul Crivelli (San Diego), Cyril Delattre (Lyons, France), Gerald Kreindl (San Diego), Wesley A. Cox-Muranami (Middleton, Wis.) and Bryan Crane (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "Actuation systems and methods for use with flow cells. In accordance with an implementation, a method includes moving, using an actuator disposed within a manifold assembly, a membrane portion of a membrane of the manifold assembly away from a valve seat to enable fluidic flow from a reagent fluidic line to a com...