US Patent Issued to ILLUMINA CAMBRIDGE on Nov. 3 for "DNA amplification buffer replenishment during rolling circle amplification" (California Inventors)

ALEXANDRIA, Va., Nov. 3 -- United States Patent no. 12,781,269, issued on Nov. 3, was assigned to ILLUMINA CAMBRIDGE Ltd. (Cambridge, Great Britain).

"DNA amplification buffer replenishment during rolling circle amplification" was invented by Nathan Jameson (San Diego), Kurt Patterson (San Diego), Fabian Block (San Diego) and Brittany Rohrman (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided include methods, compositions, kits, and systems for replenishing a rolling circle amplification (RCA) reaction in a vessel. The RCA reaction can be initiated by contacting a nucleic acid template and a primer with a loading buffer comprising a DNA polymerase and polymerase extension agents including a d...