US Patent Issued to IGM BIOSCIENCES on June 9 for "IgM Fc and j-chain mutations that affect IgM serum half-life" (California Inventors)

ALEXANDRIA, Va., June 9 -- United States Patent no. 12,649,791, issued on June 9, was assigned to IGM BIOSCIENCES INC. (Mountain View, Calif.).

"IgM Fc and j-chain mutations that affect IgM serum half-life" was invented by Ramesh Baliga (Redwood City, Calif.), Bruce Keyt (Hillsborough, Calif.) and Dean Ng (San Francisco).

According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure provides an IgM antibody or IgM-like antibody comprising a variant J-chain and/or variant IgM heavy chain constant regions that can confer increased serum half-life upon the antibody."

The patent was filed on Dec. 29, 2023, under Application No. 18/400,974.

*For further information, including images, charts and tables, please vi...