ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,497,598, issued on Dec. 16, was assigned to Hvidovre Hospital (Hvidovre, Denmark).

"Method of purifying whole virus particles" was invented by Judith Margarete Gottwein (Frederiksberg C, Denmark), Jens Bukh (Praesto, Denmark), Anna Offersgaard (Kobenhavn O, Denmark), Anne Finne Pihl (Kobenhavn O, Denmark), Michael Wolff (Wandlitz, Germany) and Keven Lothert (Giessen, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a method of purifying whole HCV particles, the method comprising the steps of a) providing a cell culture supernatant comprising virus particles, b) purification and/or concentration of the cell culture ...