US Patent Issued to Hoffmann-La Roche on Sept. 8 for "Radiolabeled MOEM type oligonucleotides and process for their preparation" (German Inventors)

ALEXANDRIA, Va., Sept. 8 -- United States Patent no. 12,728,174, issued on Sept. 8, was assigned to Hoffmann-La Roche Inc. (Branchburg, N.J.).

"Radiolabeled MOEM type oligonucleotides and process for their preparation" was invented by Martin Robert Edelmann (Lorrach, Germany) and Thorsten Muser (Lorrach, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention comprises radiolabeled MOEM type oligonucleotide of the formula (I), (I) wherein n, X1, X2, the linker (1), the linker (2), Q* and the receptor targeting moiety are as defined (I) the description. The radiolabeled oligonucleotides of the formula (I) can be used for the determination of the biodistribution and pharmacokinetics of the oligonu...