US Patent Issued to Hoffmann-La Roche on Sept. 22 for "High ionic strength dissociation assay for high drug tolerant testing" (German Inventors)

ALEXANDRIA, Va., Sept. 24 -- United States Patent no. 12,742,785, issued on Sept. 22, was assigned to Hoffmann-La Roche Inc. (Branchburg, N.J.).

"High ionic strength dissociation assay for high drug tolerant testing" was invented by Gregor Jordan (Grobenzell, Germany) and Roland Staack (Munich).

According to the abstract* released by the U.S. Patent & Trademark Office: "Herein is reported a method for the determination of the presence of anti-drug antibodies in a sample comprising the steps of incubating the sample with MgCl2 at a final concentration in the range of 1 N to 12 N; adding a tracer antibody and incubating the sample thereafter; incubating the isolated tracer antibody-anti-drug antibody-complexes with a detection antibody conj...