US Patent Issued to Hoffmann-La Roche on Oct. 27 for "Antibodies binding to CD3 and FOLR1" (Swiss, German Inventors)

ALEXANDRIA, Va., Oct. 27 -- United States Patent no. 12,774,350, issued on Oct. 27, was assigned to Hoffmann-La Roche Inc. (Little Falls, N.J.).

"Antibodies binding to CD3 and FOLR1" was invented by Peter Bruenker (Hittnau, Switzerland), Martina Geiger (Obfelden, Switzerland), Christian Klein (Weilheim, Germany) and Alexander Knaupp (Wackersberg, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention generally relates to bispecific antibodies that bind to CD3 and Folate Receptor 1 (FolR1), e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further r...