US Patent Issued to Hoffmann-La Roche on May 26 for "Fc-receptor binding modified asymmetric antibodies and methods of use" (German Inventors)

ALEXANDRIA, Va., May 26 -- United States Patent no. 12,637,506, issued on May 26, was assigned to Hoffmann-La Roche Inc..

"Fc-receptor binding modified asymmetric antibodies and methods of use" was invented by Joerg Thomas Regula (Munich), Wolfgang Schaefer (Mannheim, Germany) and Tilman Schlothauer (Penzberg, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "Herein is reported an IgG class Fc-region comprising a first variant Fc-region polypeptide and a second variant Fc-region polypeptide, wherein the first variant Fc-region polypeptide is derived from a first parent IgG class Fc-region polypeptide and the second variant Fc-region polypeptide is derived from a second parent IgG class Fc-region polypep...