ALEXANDRIA, Va., July 15 -- United States Patent no. 12,662,490, issued on June 23, was assigned to Hoffmann-La Roche Inc. (Little Falls, N.J.).

"Heterocyclic compounds" was invented by Carsten Kroll (Basel, Switzerland), Flore Reggiani (Ranspach le Haut, France), Miroslav Kosar (Urdorf, Switzerland), Maurice Biedermann (Zurich), Bernd Kuhn (Reinach, Switzerland), Benoit Hornsperger (Altkirch, France), Uwe Grether (Efringen-Kirchen, Germany), Fionn O'Hara (Basel, Switzerland) and Hans Richter (Grenzach-Wyhlen, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides new heterocyclic compounds having the general formula (I)wherein R1, R2, X, and Y are as defined herein, compositions inclu...