ALEXANDRIA, Va., July 14 -- United States Patent no. 12,679,840, issued on July 14, was assigned to Hoffmann-La Roche Inc. (Little Falls, N.J.).
"Process for the preparation of (9S)-N-[3-(6-methylpyrimidin-4-yl)-3-azabicyclo[3.2.1octan-8-yl-9-(2,3,4-trifluorophenyl)-6,7,8,9-tetrahydro-5H-[1,2,4triazolo[1,5-aazepin-2-amine and its solid form" was invented by Weichun Chen (Shanghai) and Guocai Zhang (Shanghai).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a process for the preparation of a compound (I),and its solid form, which is a modulator of Gamma-secretase and may be useful for prophylaxis and treatment of a disease associated with the deposition of Beta-amyloid in the bra...