ALEXANDRIA, Va., April 7 -- United States Patent no. 12,594,271, issued on April 7, was assigned to Health Research Inc. (Buffalo, N.Y.).
"Combination therapy for cancer" was invented by Scott I. Abrams (Amherst, N.Y.) and Sean H. Colligan (Buffalo, N.Y.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are methods for treatment of cancer. The method comprises administering to an individual who has cancer a combination of treatment to reduce MDSC burden and immune therapy. For example, an individual may be administered brequinar and an immune checkpoint inhibitor. This disclosure provides a method for redirecting early myeloid precursors away from generating MDSCs thereby reducing MDSC burden."
The pa...