ALEXANDRIA, Va., July 16 -- United States Patent no. 12,668,631, issued on June 30, was assigned to HARBOUR BIOMED (SHANGHAI) Co. LTD (Shanghai).

"CD3-targeting antibody, bispecific antibody and use thereof" was invented by Yun He (Suzhou, China) and Lei Shi (Suzhou, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are a CD3-targeting antibody, a bispecific antibody and the use thereof. The CD3-targeting antibody comprises a light chain variable region (VL) and a heavy chain variable region (VH). The VL has the amino acid sequence as shown in SEQ ID NO: 56 or a mutation thereof. The VH has mutations on the amino acid sequence as shown in SEQ ID NO: 42, and the mutations occur at one or more of ...