ALEXANDRIA, Va., April 15 -- United States Patent no. 12,600,959, issued on April 14, was assigned to Halozyme Inc. (San Diego).

"PH20 polypeptide variants, formulations and uses thereof" was invented by Ge Wei (San Diego), H. Michael Shepard (Eugene, Ore.), Qiping Zhao (San Diego) and Robert James Connor (Oceanside, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof."

The patent was filed on March 5, 2025, under Application No. 19/071,345.

*For further information, including images, charts and...