ALEXANDRIA, Va., Aug. 18 -- United States Patent no. 12,709,616, issued on Aug. 18, was assigned to Halia Therapeutics Inc..
"NEK7 inhibitors" was invented by David James Bearss (Lehi, Utah), John Sai Keong Kauwe III (Lehi, Utah) and Alexis Henri Abel Mollard (Lehi, Utah).
According to the abstract* released by the U.S. Patent & Trademark Office: "Compounds having activity as inhibitors of NEK7 are provided. The compounds have Structure (I): (I) or a pharmaceutically acceptable salt, stereoisomer, or prodrug thereof, wherein A, X, Y, Z, R1, R2, R3, and n are as defined herein. Methods associated with preparation and use of such compounds, pharmaceutical compositions comprising such compounds and methods to modulate the activity of the NLR...