US Patent Issued to HACKENSACK MERIDIAN HEALTH on Sept. 1 for "Molecular engineering to enhance CAR-T mediated tumor immunotherapy" (New Jersey, New York, Pennsylvania Inventors)

ALEXANDRIA, Va., Sept. 1 -- United States Patent no. 12,721,891, issued on Sept. 1, was assigned to HACKENSACK MERIDIAN HEALTH INC. (Edison, N.J.).

"Molecular engineering to enhance CAR-T mediated tumor immunotherapy" was invented by Hai-Hui Xue (Nutely, N.J.), Yi Zhang (Wallingford, Pa.), David Perlin (New York), Xin Zhao (Clifton, N.J.) and Wei Hu (Union City, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a chimeric antigen receptor (CAR) immunotherapy for treating a hematologic cancer comprising (a) genetically modifying a population of immune effector cells comprising T cell receptors (TCRs) to stably express at least one CAR, wherein the ectodomain of the CAR specif...