ALEXANDRIA, Va., July 16 -- United States Patent no. 12,668,776, issued on June 30, was assigned to H.LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE INC. (Tampa, Fla.).

"Artificial antigen presenting cells comprising protein L for expanding immune cells for immunotherapy" was invented by Marco Davila (Tampa, Fla.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are methods of expanding immune cells for immunotherapy and/or increasing the purity of a population of CAR T cells using artificial antigen presenting cells (aAPCs) having on their surface Protein L. The disclosed aAPCs can also secrete antibodies that bind molecules of the T cell inhibitory pathway. For example, anti-CD3 scFv on the...