ALEXANDRIA, Va., Dec. 23 -- United States Patent no. 12,502,435, issued on Dec. 23, was assigned to H. Lee Moffitt Cancer Center and Research Institute Inc. (Tampa, Fla.).
"Metastatic brain tumor targeting peptides" was invented by James K. Liu (Lutz, Fla.), Daniel Abate-Daga (Tampa, Fla.) and Cecilia Ramello (Tampa, Fla.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods are disclosed for targeted treatment of lung cancer-derived metastatic brain tumors. In particular, tumor targeting agents comprising targeting peptides are disclosed that can target a payload, such as a therapeutic or diagnostic agent, to lung cancer-derived metastatic brain tumors. Chimeric antigen receptor (CAR) poly...